*3.4. Superoxide Production*

Intravenous administration of USPIONs resulted in the significant increase of superoxide production in the liver, LHV, kidneys and aorta by approximately 110%, 101%, 54% and 66%, respectively, compared to the control group (*p* < 0.05 in all groups) as shown in Figure 19.

**Figure 19.** Superoxide production (**a**) in the liver, (**b**) left heart ventricle (LHV), (**c**) kidney and (**d**) aorta. The values represent the mean ± SEM. \* *p* < 0.05 vs. control (Cont) group.
