2.5.1. 2,4-dodecylamino-6-chloro-1,3,5-triazine

Cyanuric chloride (970 mg, 5.26 mmol) and dodecylamine (2.0 g, 10.8 mmol) were mixed in 150 mL CHCl3. The mixture was cooled with an ice bath, then 10% aqueous KOH was added up to the pH~10. The reaction mixture was stirred overnight at room temperature, then organic phase was separated, the solvent was evaporated under vacuum, and the solid residue was recrystallized from the mixture CHCl3:CH3OH (5:1) to yield the desired product as white solid (2.28 g, 90%).

1H NMR (400 MHz, CDCl3) δ 0.86 (t, J = 6.8 Hz, 6H, Ha), 1.18–1.37 (m, 32H, Hb), 1.52–1.64 (m, 8H, Hc, Hd), 3.45 (q, J = 6.8 Hz, 4H, He), 6.03 (s, 2H, Hf). 13C NMR (101 MHz, CDCl3) δ 14.1, 22.6, 26.6, 28.5–29.9 (m), 31.9, 41.5, 165.8, 169.7, 171.0. MS: [M + H]<sup>+</sup> 482.40 amu (calcd 481.39 amu).
