**4. Conclusions**

In this work, the incorporation of solid and aqueous magnetoliposomes in supramolecular hydrogels was assessed in three different gels through a pH trigger. It was demonstrated that, upon the incorporation of the magnetoliposomes, the encapsulated molecules distributed to a similar environment independently of the magnetoliposome architecture. Further, magnetoliposomes can be saturated with the required drug, as the hydrogel displays hydrophobic cavities that accommodate the excessive drug amount, which can be explored as a way to avert the premature release of the administered drug. This system design approach provides a useful strategy to increase the array of drugs that can be encapsulated compared to magnetic gels and magnetoliposomes alone. Concerning the discussed findings in this communication, research is being carried out to assess the influence of the different magnetic lipogel architectures on drug delivery control and tunability, as well as to evaluate its impact on hyperthermia capability.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/2079-4991/10/9/1702/s1, Figure S1: Stability of Nanoparticles and Magnetoliposomes Dispersions, Figure S2: SEM Image of Solid Magnetoliposomes, Figure S3: Curcumin Release Assay.

**Author Contributions:** Conceptualization, S.R.S.V. and E.M.S.C.; methodology, P.M.T.F., J.A.M., P.J.G.C. and E.M.S.C., validation, A.R.O.R., J.A.M., P.M.T.F. and E.M.S.C.; formal analysis, S.R.S.V., R.G.D.A., A.R.O.R. and E.M.S.C.; investigation, S.R.S.V., R.G.D.A., B.C.R. and A.V.F.F.; writing—original draft preparation, S.R.S.V. and E.M.S.C.; writing—review and editing, P.J.G.C. and E.M.S.C.; supervision, P.M.T.F. and E.M.S.C.; project administration, P.J.G.C. and P.M.T.F. All authors have read and approved the final version of the manuscript. **Funding:** This work was supported by the Portuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Funding of CF-UM-UP (UIDB/04650/2020) and CQUM (UIDB/00686/2020). FCT, FEDER, PORTUGAL2020 and COMPETE2020 are also acknowledged for funding under research projects PTDC/QUI-QFI/28020/2017 (POCI-01-0145-FEDER-028020) and PTDC/QUI-QOR/29015/2017 (POCI-01-0145- FEDER-029015). S.R.S.V. acknowledges FCT for a PhD grant (SFRH/BD/144017/2019) and MAP-Fis PhD program for support.

**Conflicts of Interest:** The authors declare no conflict of interest.
