*2.3. Neurodegenerative Diseases*

Neurons are fundamental units of the brain and play a significant role in coordinating the actions and reactions of bodily functions. These neurons are highly vulnerable to ROS, as they weaken the antioxidants defense system, elevate the fatty acid (polyunsaturated) content in the cell membrane and increase the oxygen demand [36]. The significant research conducted in this direction revealed that ROS generation takes place through numerous mechanisms, and play a vital role in developing neurodegenerative diseases like Alzheimer's, Huntington's and Parkinson's disease. These ROS considerably affects the neuron and other cellular processes, the controlling of ROS level may serve as a potential treatment to restrain neurodegenerative disorder and provide relief from its associated symptoms [37].
