**4. Discussion**

The use of liposomes in dialysate is in varying stages of preclinical development and is focused on areas of currently unmet clinical need. Liposomes in dialysate may increase the "reach" of dialysis for protein-bound molecules in blood and increase the total extraction capacity of peritoneal dialysate for ammonia. Larger doses of liposome are able to be used in dialysate than could be given intravenously as dialysate is in a compartment separated from complement surveillance. It is conceivable that liposomes will be repurposed from the role of pharmaceutical vectors to gain further indications as clinically useful nanomedical antidotes/treatments within the next decade.

Discussions categorised by the class of liposome target are outlined below.
