*3.9. Ocular Compatibility*

*3.9. Ocular Compatibility* Eye irritation score from individual rabbits was added to obtain the total irritation score, which was subsequently divided by the total number of eyes used for the ocular irritancy test to obtain the final eye irritation score. The calculated eye irritation score in Eye irritation score from individual rabbits was added to obtain the total irritation score, which was subsequently divided by the total number of eyes used for the ocular irritancy test to obtain the final eye irritation score. The calculated eye irritation score in CL10 was 0.50, while it was 0.17 in the reference. The irritation score observed in CL10 was relatively low and could be classified as practically non-irritant [57]. Further, instillation of CL10 did not cause redness, swelling, or excessive lachrymation in the eye. Overall, the data signified that CL10 is safe and non-irritant for ocular administration.
