2.5.1. Particle Size Characterization and Zeta Potential

Particle size analysis, polydispersity index, and zeta potential of the clarithromycinloaded SLN were determined using a zetasizer (Nanopartica SZ-100, Horiba, Kyoto, Japan). To perform the test, drops (2–3) of test samples placed in the disposable cuvette were exposed to the laser beam. The intensity and physical characteristics of scattered light were measured with the detector, and the particle sizes were subsequently determined [27]. The electrophoretic mobility values were measured after suitable dilution with water at 25 ◦C.
