*3.1. Analysis of the DSPE–HA Conjugate*

The DSPE–HA conjugate was analyzed with <sup>1</sup>H-NMR and FT-IR spectroscopy (Figure S1, Supplementary Materials). The <sup>1</sup>H-NMR spectra showed the typical peaks for DSPE–HA sugar rings (3–4 ppm), *N*-acetate (1.7–2 ppm), methylene (~1.2 ppm), and terminal methyl (~0.9 ppm) as reported by other groups [32,36]. DSPE and DSPE–HA were analyzed with FT-IR. The DSPE–HA spectra showed comparable peaks (3366, 2918, 2853, 1730, and 1643 cm−<sup>1</sup> ) with both the HA and the DSPE spectra in accordance with a previous report by Yao et al. [32]. The analysis confirmed the successful production of the DSPE–HA conjugate.
