*2.1. Materials*

Fluconazole was purchased from Sigma-Aldrich Co. (St Louis, MO, USA). Tween 20® was acquired as a generous gift from Saudi Drugs and Medical Instruments Company (SPIMACO), in Qassim, Saudi Arabia. Sesame oil and Lecithin were procured from Avanti Polar Liquids (Alabaster, AL, USA). High-performance liquid chromatography (HPLC) grade solvents were collected form Merck (Darmstadt, Germany). All other reagents and chemicals used were of analytical grade.
