*2.8. In Vitro Gastrointestinal Lipolysis Studies*

For the present study, a combined gastrointestinal (GI) in vitro lipolysis model adapted from [37] was employed to test solubilization of FEN under digesting conditions. FaSSIF/FeSSIF/FaSSGF powder was used to prepare gastric (FaSSGF) and intestinal (FaSSIF) media, according to manufacturer's protocol (biorelevant.com, London, UK). Media were freshly prepared before each experiment and used within 48 h, according to manufacturer's recommendations.
