*2.8. Characterization of Dispersed SEDDS*

The dispersions of both Citrem and Standard SEDDS were characterized in terms of size and polydispersity index (PdI) by dynamic light scattering; zeta potential was measured by laser Doppler electrophoresis using Zetasizer Nano ZS (Malvern Instruments, Worcestershire, UK). The dispersions of blank and complex-loaded SEDDS were dispersed 1:100 (*w*/*w*) in DI water and 10-mM MES-HBSS buffer (pH 6.5) immediately before the experiment and evaluated at 37 ◦C. Data were collected in triplicate.
