**5. Conclusions**

We measured a single-channel EEG non-invasively during CPR and evaluated the relationship between EEG parameters and the CBF recovery. Our findings indicated that time-domain magnitude and entropy indices of EEG, even during the brief pause in CPR, may correlate with the level of cerebral circulation. Further studies are warranted to evaluate these parameters as potential markers of cerebral resuscitation.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/1424-8220/20/11/3052/s1, Figure S1. Experimental setup; Figure S2. The entire test scenario; Figure S3. Comparison of EEG over time between ROSC and non-ROSC cases; Figure S4. Scatter plots between EEG parameters and the recovery of CBF. Correlation coefficients were denoted above the plots; Figure S5. Results of one-way ANOVA; Figure S6. ROC curves (blue) for three EEG parameters; Table S1. EEG parameters considered in this study; Table S2. Pearson correlation coefficients between EEG parameters and the recovery rates of CBF; Table S3. Results of multiple comparisons between groups in three EEG parameters; Table S4. Results of the ROC curve analysis for EEG parameters; Supporting File S1. Hemodynamic changes of individual animals throughout the experiments.

**Author Contributions:** H.K. conceived of the presented idea, analyzed the data and wrote the manuscript. Y.K. supervised the findings of this work and contributed to the final version of the manuscript. K.H.K. and K.J.H. carried out the animal experiments. S.D.S. and H.C.K. contributed to the design and implementation of the research. All authors discussed the results and approved the final manuscript.

**Funding:** This study was supported by the Encouragement Program for the Industries of Economics Cooperation Region, funded by South Korea's ministry of Trade, Industry and Energy (Grant Number: R0004491), and by the research fund of Chungnam National University.

**Conflicts of Interest:** The authors declare no conflict of interest.
