**5. Conclusions**

In our e fforts to expand the scope of a generalized approach to forming chiral lantern-type cages, complexes containing paddlewheel and "pseudo-paddlewheel" motifs were synthesized using the chiral diacids **H2L1** and **H2L2**. The [Cu4(**L1**)4] cage adopts the anticipated lantern-type helical structure with a larger central cavity than our previously reported sulfone-based cage (ca. 380 Å3). The cages within the [{Co4(**L2**)4(DABCO)(H2O)x}2(DABCO)] complexes retain the overall general design but are clearly under some strain, highlighted by the broken paddlewheels at their extremities. These results show promising initial steps towards a generic approach for the formation of enantiopure helical compounds, with the condition/limitation that the core group of the ligand contains the correct angular preference and flexibility. These results are encouraging to our ongoing e fforts to expand the structural types accessible from this general approach.

**Author Contributions:** Conceptualization, D.R.T.; methodology, S.A.B. and D.R.T.; investigation, S.A.B., W.C., B.K.G. and D.R.T.; writing—original draft preparation, D.R.T.; writing—review and editing, S.A.B., W.C., B.K.G. and D.R.T.; supervision, D.R.T.; project administration, D.R.T.; funding acquisition, D.R.T. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research was partly funded by the Australian Research Council, gran<sup>t</sup> number FT120100300.

**Acknowledgments:** Part of this work was conducted using the MX1 beamline at the Australian Synchrotron, part of ANSTO.

**Conflicts of Interest:** The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

*Chemistry* **2020**, *2*
