*3.6. WGM Derived Genomic Rearrangements*

SVs were identified relative to the human reference genome, GRCh38, whose genome maps were bioinformatically deduced based on predicted Nt.BspQI (GCTCTTCN) or DLE-1 (CTTAAG) motif sites. SV detection was performed as part of the Bionano Solve pipeline. Details of the underlying algorithm are described in the software's accompanying documentation (Document # 30110B).
