*4.6. Western Blot*

DONSON knockdown efficiency was assessed 72h post-transfection. The following antibodies were used: Anti-DONSON (1:1000, LS-C167506, Rabbit, LSBio, Seattle, WA, USA); Anti-alpha-Tubulin (1:4000, A5316, Mouse, Sigma-Aldrich, St. Louis, MO, USA).

#### *4.7. Cell Proliferation Assays*

We used the EZ4U cell proliferation and cytotoxicity assay kit according to the manufacturer's protocol (EZ4U, Biomedica Group, Vienna, Austria).
