2.5.2. Mechanical Properties

Tests were conducted with friability tester (EF-1 W, Electrolab, Mumbai, India) according to pharmacopoeial monograph for a quantity of ODMT corresponding to 6.5 g [25]. The crushing strength of ODMT was tested utilizing a hardness tester (5Y, Pharmaton AG, Thun, Switzerland) and a Texture Analyzer TA.XT. Plus (Stable Microsystems, Godalming, UK) with a steel cylinder of 6 mm diameter and 0.1 mm/s pre-speed [25]. The minimum force (N) needed to crush the ODMT was measured by vertically applying pressure along its diameter. Ten randomly selected tablets from the batch were used for hardness assessment in both methods.
