*2.2. Western Blots*

Proteins were extracted, denatured, and immunoblotted as previously described [41]. Detection antibodies used were anti-LMP2A clone 15F9 (Biorad, Hercules, CA, USA), anti-LMP1 clone CS 1-4 (Abcam, Cambridge, UK) and a polyclonal anti-EBNA1 antibody (Invitrogen, Carlsbad, CA, USA). Secondary anti-rat, -mouse, and -goat antibodies conjugated to horseradish peroxidase were used for visualization. Anti-β-actin (a5441, Sigma-Aldrich, St. Louis, MO, USA) was used as a loading control. Images were captured using an ImageQuantLAS 4000 (GE Healthcare Life Sciences, Marlborough, MA, USA).
