*2.1. Inactivated Viral Vaccine, Lipid Adjuvants, and Formulations*

Whole inactivated viral (WIV) vaccines are whole viral particles that are inactivated with formalin [22]. The influenza strain A/H1N1/Salomon Island/2006 (A/H1N1/SI) was used as a model vaccine candidate. The adjuvant N3 is based on a natural human fatty acid (L3) that is composed of: oleic acid 92%, linoleic acid 6%, and saturated monoolein 2% [23], and modified by coupling an amine-group to obtain a charged cationic molecule, N3 [24].
