*2.8. Statistics*

GraphPad Prism 7 and 8 were used to perform statistical analyses. The two-tailed unpaired Student's t test was used to calculate differences between means of experimental groups, with the Mann–Whitney test for non-parametric distributions. One-way analysis of variance (ANOVA) was used for comparisons between more than one group, with Kruskal-Wallis used in cases of nonparametric distributions. Error bars in all graphs show the standard error of the mean. The log-rank test was used to compare survival rates. *p* < 0.05 was considered statistically significant.
