*2.15. Statistical Analysis*

Statistical analysis was performed with Statistica 6 software (StatSoft Inc., Tulsa, OK, USA). Prism 5 software (GraphPad5, SanDiego, USA) was used to create graphs. Data was presented as means ± SD (standard deviation) of three independent experiments and analyzed by two-tailed Student t-test or one-way analysis of variance (ANOVA), followed by Tukey tests for multiple comparisons, when appropriate (*p* < 0.05 was considered as statistically significant).

#### **3. Results**
