**5. Conclusions**

This study demonstrated the anti-proliferative effects of CAP on endothelial HDMEC, which depend on the duration of treatment and are due to the induction of apoptosis by CAP. In addition, it was shown that the migration of endothelial cells could be inhibited directly by CAP. The results of this work show that CAP is used to suppress angiogenesis and that tumor growth and the metastatic spread of malignant tumors can be directly influenced.

**Author Contributions:** Conceptualization, D.G., M.B.S. and A.E.; methodology, L.H. and O.N.; software, A.N.; validation, P.H., A.N., M.B.S. and S.B.; formal analysis, D.G., A.N. and L.H.; investigation, O.N., L.H., N.C.K. and S.B.; resources, A.M., A.E. and P.H.; data curation, M.B.S., N.C.K. and O.N.; writing—original draft preparation, L.H., A.N. and O.N.; writing—review and editing, L.H., N.C.K. and M.B.S.; visualization, O.N., N.C.K. and A.N.; supervision, D.G., A.E., A.M. and P.H.; project administration, A.M., P.H. and A.E.; All authors have read and agreed to the published version of the manuscript.

**Funding:** No external funding.

**Conflicts of Interest:** The authors declare no conflict of interest.

## **Abbreviations**

