**6. Patents**

1. E.A. Zherebtsov, I.O. Kozlov, A.I. Zherebtsova, E.V. Zharkikh, Y.I. Loktionova and A.V. Dunaev, "Software for data analysis of multi-channel wearable device for recording the level of capillary blood flow." Software patent RU 2019665950 (2019).

2. I.O. Kozlov and E.A. Zherebtsov, "Software for recording the distribution of blood perfusion by Doppler shift frequencies." Software patent RU 2019616389 (2019).

**Author Contributions:** Conceptualization, methodology, investigation, discussion, writing—review and editing, A.A.F.; writing—original draft preparation, formal analysis, Y.I.L.; writing—original draft preparation, discussion, E.V.Z.; investigation, data curation, M.A.M.; investigation, J.A.P.; methodology, investigation, A.V.S.; discussion, funding acquisition, project administration, formal analysis, E.A.Z. All authors edited the manuscript. All authors have read and agreed to the published version of the manuscript.

**Funding:** The reported study was funded by the Russian Foundation for Basic Research (RFBR), gran<sup>t</sup> number 20-08-01153. A. Fedorovich, J. Popova and A. Suvorov were funded in the framework of the research topic 64.1 by the Russian Academy of Science (RAS). E. Zherebtsov acknowledges the funding from the Academy of Finland, gran<sup>t</sup> number 318281.

**Institutional Review Board Statement:** The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of Institute of Biomedical Problems of the Russian Academy of Sciences (protocol code 483, 3 August 2018).

**Informed Consent Statement:** Informed consent was obtained from all subjects involved in the study.

**Data Availability Statement:** The data presented in this study are available on request from the corresponding author.

**Acknowledgments:** The authors express their acknowledgements to all the volunteers who contributed to the present study.

**Conflicts of Interest:** The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
