**5. Conclusions**

Treatment with Bean-PS attenuated the TMT-induced memory impairment in the MWM test. Furthermore, the Bean-PS improved cognitive function, and generated a neuroprotective effect by increasing the expression of cholinergic neurons and glucose metabolism. Thus, Bean-PS is a potential agent that can be used to prevent and protect against neurodegenerative diseases such as dementia and AD. It may represent a good therapeutic agent for of the management of AD.

**Author Contributions:** Conceptualization, M.Y., K.K., and I.S.; Data curation, M.Y., J.S.K., and B.H.H.; Formal analysis, M.Y., J.S.K., and B.H.H.; Investigation, M.Y., K.K., and I.S.; Methodology, M.Y., J.S.K., and I.S.; Project administration, K.K., and I.S.; Software, M.Y. and J.S.K.; Validation, M.Y. and J.S.K.; Writing—original draft, M.Y.; Writing—review & editing, M.Y., K.K., and I.S. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was supported by the Korean Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET 11080-03-3-HD020), funded by the Ministry of Agriculture, Food and Rural Affairs (MAFRA).

**Conflicts of Interest:** The authors have no conflicts of interest to declare. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
