*4.11. Statistical Analysis*

Results are expressed as mean ± SEM of (*n*) independent animals. Statistical analysis was performed with the GraphPad Prism software, version 6.01 (La Jolla, CA, USA). Before analysis, the Shapiro–Wilk test was used to test normality. One-way ANOVA followed by the Newman–Keuls multiple comparison test were performed. Differences were considered significant when *p* ≤ 0.05.
