**4. Conclusions**

This study demonstrates that CS-GT has e fficient antimicrobial properties, as evidenced by viability assay and hemolysis assay of L929 cells that CS-GT is not cytotoxic and has good cytocompatibility and hemocompatibility. With CS-GT as an active repair component and PVP as the matrix, CS-GT hydrogel was prepared. The application of this hydrogel enabled quicker scald healing and shorter healing time in animals. Biochemical analysis shows that by facilitating the synthesis of TP and HYP in granulation tissue, CS-GT hydrogel promoted collagen fibrosis while reducing cytokine levels in an inflammatory response, and thereby accelerated wound healing. All these results demonstrate that CS-GT hydrogel is a promising e fficient novel scald repair dressing.

**Author Contributions:** Conceptualization, S.K., C.L., T.Y., S.L., and Y.C.; data curation, T.Y., Q.O., and T.H.; formal analysis, S.K., C.L., and T.Y.; funding acquisition: S.L., S.K., and C.L.; investigation, T.Y., Q.O., T.H., S.K., C.L., S.L., and Y.C.; methodology, S.K., T.Y., and C.L.; Project administration, S.K., C.L., S.L., and Y.C.; supervision, S.K., S.L., and C.L.; validation, T.Y., Q.O., and T.H.; visualization, T.Y., Q.O., and T.H.; writing—original draft, T.Y., Q.O., and S.K.; writing—review and editing, S.K. and T.Y. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was supported by the National Natural Science Foundation of China (No. 81803684), the Natural Science Foundation of Guangdong Province (No. 2018A030313416 and No. 2020A1515011011), the Project of Science and Technology Plan of Guangdong Province (No. 2015A020216019 and No. 2017A010103023), the Project of Enhancing School With Innovation of Guangdong Ocean University (No. GDOU2013050221 and No.GDOU2016050255), and the Team Project of Innovation and Entrepreneurship for Undergraduates of Guangdong Ocean University (No. CCTD201828).

**Conflicts of Interest:** The authors have declared no conflicts of interest.
