**4. Conclusions**

Melon-seed oil is proposed as a highly valuable product that can be obtained from the byproducts of the agroindustrial processing of melons. This oil showed a high content of polyunsaturated fatty acids, mainly linoleic, and a high concentration of vitamin E. However, the effect of cultivar and oil-extraction method must be considered, as they have crucial influence in melon-oil characteristics. The oil-extraction method influences oil-quality parameters and oil due to the processing temperature in screw-press extraction. However, low yields obtained by hydraulic-press extraction could be inconvenient for industries to obtain an economic benefit. On the other hand, the use of different cultivars results in oils with different degrees of unsaturation and vitamin E content. Regarding vitamin E content, melon-seed oil may be considered as a rich source of tocopherols and tocotrienols. The industrial extraction of oil from melon seeds is a feasible option to obtain high-quality oil in order to meet the current demand of vegetable oils for human nutrition.

**Author Contributions:** Conceptualization, A.R. and M.Á.-O.; methodology, M.A.N., M.B.P.P.O., and M.Á.-O.; formal analysis, M.A.N., S.M.F.B., and M.Á.-O.; investigation, A.R., M.A.N., and M.Á.-O.; resources, A.R., J.E.P., and M.B.P.P.O.; data curation, A.R., M.A.N., and S.M.F.B.; writing—original-draft preparation, A.R.; writing—review and editing, M.Á.-O.; visualization, J.E.P. and M.B.P.P.O.; supervision, J.E.P. and M.B.P.P.O.; project administration, J.E.P.; funding acquisition, A.R., J.E.P., and M.B.P.P.O. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research was partially supported by a gran<sup>t</sup> from the University of Castilla-La Mancha (ref. [2015/4062]) and by a project from the Castilla-La Mancha Regional Government (FEDER-SBPLY/19/180501/000047).

**Conflicts of Interest:** The authors declare no conflict of interest.
