**5. Conclusions**

In summary, the association of two genetic mutations confers an independent risk for VTE in NS. Therefore, genetic testing for inherited thrombophilia in NS could play an important role in detecting high-risk patients that warrant prophylactic anticoagulation.

**Author Contributions:** Conceptualization, G.I., B.O., R.J., B.S. and A.A.; methodology, B.O.; formal analysis, B.O.; data curation, R.J. and A.A.; writing—original draft preparation, G.I. and B.O.; writing—review and editing, G.I., B.O., B.S., R.J., A.A., M.H.; supervision, G.I. and M.H. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Conflicts of Interest:** The authors declare no conflict of interest.
