**1. Introduction**

Pregnant women with chronic kidney disease (CKD) are at high risk of adverse maternal and fetal outcomes, such as preeclampsia, low birth weight and death, even in cases of mild CKD [1,2]. Moreover, pregnancy itself is a risk factor for CKD progression [3]. Preeclampsia is both a systemic and hypertensive disorder in pregnancy. Estimated to complicate 2–8% of all pregnancies, it is a leading cause of maternal and perinatal morbidity and mortality [4]. According to previous studies, preeclampsia superimposed on chronic hypertension and CKD are estimated to occur in 26% and 21–79% of pregnancies, respectively [5,6]. Preeclampsia superimposed on CKD is challenging for the clinician because both conditions share common features such as proteinuria and hypertension, making differential diagnosis difficult [7]. There is some evidence regarding biomarkers associated with preeclampsia in pregnant women with CKD, but further studies are needed in this regard [8]. The aim of this study was to evaluate the incidence and clinical and biological predictors of preeclampsia in pregnant women with CKD.
