**5. Conclusions**

The purpose of the oral GVHD treatment is to reduce symptoms, maintain or improve the quality of life and reduce complications. Topical corticosteroids are most frequently used when oral tissues are the sole site of involvement. Based on the clinical trials, all three agents seem to be effective in treating oral GVHD and have a satisfactory safety profile. More RCTs with larger cohorts are needed to assess the efficacy of this topical agents.

**Author Contributions:** Conceptualization, A.S., A.P., S.P. and A.M.; methodology, A.S., A.P., S.P. and A.M.; validation, C.T.; investigation, A.P., S.P. and A.M. writing—original draft, A.S., A.P., S.P. and A.M.; writing—review and editing, A.S., A.M. and C.T.; supervision, C.T. All authors have read and agreed to the published version of the manuscript.

**Funding:** This study did not receive funding.

**Conflicts of Interest:** The authors declare no conflict of interest.
