**2. Materials and Methods**

The present scoping review was conducted in conformity with the Joanna Briggs Institute (JBI) and PRISMA method guidelines to identify the most recent relevant publications related to the effect of music on brain activity and emotional state in digital therapies programs. To ensure a comprehensive number of documents with significant evidence for the intended analysis, the research equation was elaborated: music AND (electroencephalography OR electroencephalogram OR EEG) AND emotion\* AND ("digital therapies" OR "digital therapy" OR "digital treatment"). The research was carried out in scientific databases B-On, Google Scholar and Semantic Scholar, during May of 2021.

### **3. Results**

The study flow diagram is presented in Figure 1. Initially, a sample of 585 documents were collected, and after removing the duplicates, 570 documents were obtained. After analyzing each document based on the theme and summary, the sample was reduced to

180 selected articles. Subsequently, and after applying the inclusion criteria, a sample of six articles were obtained to be mapped.

**Figure 1.** Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram for the scoping review process. Adapted from Moher D, Liberati A, Tetzlaff J, Altman DG: The PRISMA Statement. PLoS Med 6(7): e1000097. https://doi.org/10.1371/journal.pmed.1000097.

From Table 1, it is possible to analyze the selected documents that correspond to all the requirements defined in the research process.


**Table 1.** Mapping of scientific articles based on requirements defined in the study.


**Table 1.** *Cont.*

#### **4. Discussion and Conclusions**

In this scoping review, the authors identified six recent and relevant publications related to the effect of music on brain activity and emotional state in digital therapy programs. To cover the concepts that involve the subject of the study, four research terms were defined: "Music", "Electroencephalography", "Emotion" and "Digital Therapies".

This study identified relevant publications that describe very revealing studies on the importance of music as a therapeutic element in mental health and well-being areas.

**Author Contributions:** Conceptualization, J.C., P.V.G.; methodology, J.C., P.V.G.; validation, P.V.G.; investigation, J.C.; writing—original draft preparation, J.C.; writing—review and editing, J.C., P.V.G.; visualization, J.C., P.V.G.; supervision, A.M., J.P.; project administration, J.C. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Acknowledgments:** This research was carried out and used the equipment of the Psychosocial Rehabilitation Laboratory (LabRp) of the Research Center in Rehabilitation of the School of Allied Health Technologies, Polytechnic Institute of Porto.

**Conflicts of Interest:** The authors declare no conflict of interest.

