*3.2. Study Characteristics*

The general characteristics of the included studies (eReferences in the Supplement) were summarized in Table S1. A total of 39,501 study participants were assigned to receive 14 different treatments including 12 targeted therapies, 1 chemotherapy, and 1 dummy. Sixty-four % of all the studies involved the comparisons between EGFR-targeted drugs and other treatments.
