*2.3. Statistical Analysis*

Statistical analyses were performed using EZR statistical software, version 1.30 [9]. All statistical tests were two-sided, and *p*-values<0.05 were regarded as statistically significant. The cutoff values for body mass index (BMI), albumin, lactate dehydrogenase (LDH), neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), platelet to lymphocyte ratio (PLR), and C-reactive protein (CRP) following prior therapy were determined according to previous reports [10–15]. The PFS and OS were calculated using the Kaplan–Meier method, and differences were compared using the log-rank test. The hazard ratios (HRs) and their 95% confidence intervals (CIs) were estimated using the Cox proportional hazards model in univariate analyses. The Cox proportional hazards model was also used for the multivariate analyses.
