*3.3. Network Geometry*

Figure 1 shows the network geometry for ORR and PFS to represent graphical comparisons among various treatments. The comparative efficacy between erlotinib vs. chemotherapy/bevacizumab vs. dummy/erlotinib vs. dummy was frequently investigated for ORR, while the comparative efficacy between erlotinib vs. chemotherapy/gefitinib vs. chemotherapy/gefitinib vs. dummy/bevacizumab vs. dummy/erlotinib vs. dummy was done for PFS.

**Figure 1.** Network geometry of comparisons for overall response rate (ORR) and progression-free survival (PFS).
