*3.1. Studies Included in the Meta-Analysis*

A total of 80 records from PubMed were screened. Three additional studies presented at the WCLC and/or ESMO were also included. Study selection and exclusion criteria are summarized in Figure 1. Finally, seven clinical trials carried out with 4562 patients met the inclusion criteria and were included in the MA [17,20–25,28,29]. In the specific case of CheckMate-227, part 1 [30] was excluded because immunotherapy-plus-chemotherapy efficacy evaluation was not part of the main objectives; only part 2 was considered for this MA [21].
