**6. Conclusions**

This review covered the role of surgical intervention for unresectable NSCLC. Although many problems still need to be solved, while systemic treatments with high response rates such as TKI and/or ICI are being developed further, the importance of surgical treatment is expected to expand.

**Author Contributions:** Writing—original draft preparation, S.S.; Writing—review and editing, T.G. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Conflicts of Interest:** The authors declare no conflict of interest.
