*6.4. Type 1 Diabetes Mellitus*

Insulin therapy is the mainstay of treatment for type 1 diabetes mellitus due to ICI treatment, and immediate treatment must be initiated. If ketosis or ketoacidosis is present, immediate-acting insulin should be continuously administered, along with intravenous saline infusion and electrolyte management. After the ketosis or ketoacidosis has improved, the patient can be switched to insulin therapy. Once insulin treatment reduces the blood glucose levels, ICI treatment can be resumed.
