*Article* **Adsorption on Ligand-Tethered Nanoparticles**

**Małgorzata Borówko \* and Tomasz Staszewski**

> Department of Theoretical Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, 20-031 Lublin, Poland; staszewski@umcs.pl **\*** Correspondence: borowko@hektor.umcs.lublin.pl

**Abstract:** We use coarse-grained molecular dynamics simulations to study adsorption on ligandtethered particles. Nanoparticles with attached flexible and stiff ligands are considered. We discuss how the excess adsorption isotherm, the thickness of the polymer corona, and its morphology depend on the number of ligands, their length, the size of the core, and the interaction parameters. We investigate the adsorption-induced structural transitions of polymer coatings. The behavior of systems involving curved and flat "brushes" is compared.

**Keywords:** hairy nanoparticles; adsorption on nanoparticles; nanocarriers; molecular dynamics; computer simulations
