**5. Conclusions**

Although the relationship between microbiota and pancreatic diseases is an innovative and inspiring field of research, several points warrant further clarification. At present, the association between pancreatic diseases and microbiota is not well established. Hence, the correlation between microbiota and pancreas remains fraught with challenges. Given the potential role of microbiota in the pancreatic diseases, technological improvement in microbiota manipulation as well as randomized controlled trials could represent a powerful therapeutic strategy for their prevention and treatment.

**Author Contributions:** Conceptualization, C.G.D.A.; methodology, M.G. and F.R.; literature search, S.R. and F.C.; writing—original draft preparation, M.G., F.R., S.B.; writing—review and editing, M.G. and F.R., C.G.D.A.; supervision, G.M.S. and C.G.D.A. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Conflicts of Interest:** The authors declare no conflict of interest.
