*2.3. Repetitive mTBI Did Not Affect the Barnes Maze Task in Wild-Type and TDP-43G348C Mice at 6 Months Following Repetitive mTBI*

To explore the long-term effects of repetitive mTBI on the function of the visual system, we trained experimental animals in the Barnes maze. Figure 6 shows the latency time to reach the target hole and the time spent inside the target quadrant during the tests and the retests for all the experimental groups of mice. There was no significant difference in

the latency time to reach the target hole between the experimental groups of mice during the tests (*p* = 0.148) and the retests (*p* = 0.763) (Figure 6A,B). Additionally, no statistically significant differences in the time spent in the target quadrant between the experimental animals were obtained for the tests (*p* = 0.527) and the retests (*p* = 0.381) (Figure 6C,D).

**Figure 6.** Barnes maze task performance in wild-type (WT) and TDP-43G348C mice at 6 months after repetitive mild traumatic brain injury (rmTBI). The histogram shows the latency time (s) to reach the target hole during (**A**) the tests and (**B**) the retests or the time (s) spent in the target quadrant during (**C**) the tests and (**D**) the retests for mice with rmTBI (-) and related control groups (). Results are expressed as means ± SEM (*N* = 12–14).
