**6. Conclusions**

This study indicates that the lockdown had a significant negative impact on female mental health. Despite the increasing symptomatology during the quarantine among female students, the results suggest that it quickly disappeared after the lifting of the quarantine. Overall, the present study provides new insights into the impact of the pandemic on students' mental health and supports data about psychological distress among university students. Moreover, it gives new perspectives in the field of help-seeking behaviour. Awareness of these topics can be helpful to encourage universities to integrate mental health into their culture and implement preventive and support interventions.

**Supplementary Materials:** The following are available online at https://www.mdpi.com/article/10 .3390/ijerph18189897/s1, Table S1: Protocol of intervention, Figure S1: Mean (SD) score by female groups, Figure S2: Mean (SD) score by male groups.

**Author Contributions:** Conceptualization, M.D.C. and A.C.; Data curation, M.D.C.; Formal analysis, M.D.C., S.M. and A.C.; Investigation, M.D.C., S.M. and A.C.; Methodology, M.D.C., S.M., T.P., C.V. and A.C.; Supervision, A.C.; Writing—original draft, M.D.C. and A.C.; Writing—review and editing, M.D.C., S.M., T.P., C.V. and A.C. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Institutional Review Board Statement:** The study was conducted according to the guidelines of the Declaration of Helsinki. NoiBene protocol was approved by the local Ethical Committee of the Department of Psychology, Sapienza University of Rome (protocol code n. 0000513).

**Informed Consent Statement:** All participants signed an informed consent form regarding the research protocol, data protection and privacy according to the General Data Protection Regulation (GDPR; EU 2016/679).

**Data Availability Statement:** Group-level information about the data is available from the corresponding author on reasonable request.

**Conflicts of Interest:** M.D.C., S.M. and A.C. are members of the NoiBene Team and contributed to the development of NoiBene. A.C. is the scientific director of NoiBene. Other authors declare that there is no conflict of interest.
