**Tjalf Ziemssen**

Prof. Dr. Tjalf Ziemssen graduated in medicine from the medical schools of Bochum, Bern and London in 1998. Between 1998 and 2000, he finished his postgraduate neurological training in the Department of Neurology, University Clinic Dresden, Germany. In 1999, he completed his doctoral thesis in the laboratory of Prof. Michael Krieg (Institute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, University of Bochum.). Between 2000 and 2003, Dr. Ziemssen was post-doctoral fellow of the Deutsche Forschungsgemeinschaft (DFG) and Max-Planck-Society (MPG) at the Max-Planck Institute of Neurobiology, Department of Neuroimmunology, within the groups of Prof. Reinhard Hohlfeld, Prof. Hartmut Wekerle and Dr. Antonio Iglesias. He is currently director of the Center of Clinical Neuroscience and vice-director and consultant at the Neurological University Clinic in Dresden, head of the Autonomic Lab and MS center in Dresden. He has published more than 350 papers up to now and received several awards (e.g., of the European Charcot foundation, of the German Ophthalmological Society, of the German Parkinson Society). In 2011, he received the professorship for clinical neuroscience at a new established Center at Technische Universitat Dresden. ¨ One important research area is personalized medicine and digital neurology applying the use case of multiple sclerosis. Multidimensional patient phenotyping applying AI has been introduced into the concept of MS digital twin to predict disease course and treatment response, which is component of several ongoing projects.

#### **Rocco Haase**

Rocco Haase graduated in psychology from Technische Universitat Dresden in 2014. Already ¨ as a student, he joined the Center of Clinical Neuroscience at the Neurological University Clinic Dresden. At the moment, he is heading the research group "eHealth and analytics" and has published more than 50 papers. His multi-professional research team works on solutions to simplify patient, treatment and study management using software approaches. An eHealth portal solution is adapted to the medical requirements of the patient, integrates various participants in health care, supports necessary care models and thus makes medical and supplementary care services efficiently usable. In addition, his research is directed to the still unexplained aspects of neurological diseases using elaborated statistical and psychometric methods.
