*1.5. Other Approaches*

The zeolite clinoptilolite is well-known for its powerful antioxidant activity as a dietary supplement in bees infected with *N. ceranae*. Using clinoptilolite has resulted in significant therapeutic effects on honey bees that are naturally infected with *N. ceranae*, without affecting bee physiology [80].

Many beekeepers prefer the use of a natural approach for the treatment of nosemosis. This is no accident, as prolonged use of antibiotics will inevitably lead to resistance, pollute the environment and honey bee products, which will consequently affect human health as well.

Inspired by the use of natural compounds for *N. ceranae* treatment, we decided to test two new herbal supplements, NOZEMAT HERB® (NH) and NOZEMAT HERB PLUS® (NHP), and their influence on *N. ceranae* infection and honey bee health and survival. We believe that this study will contribute to establishing the most effective approaches against nosemosis without a negative impact on the physiological state of the bee colonies and the resulting bee products.
