ANXA1 as Endometriosis Inducing Factors

The involvement of predisposing factors in endometriosis was investigated by adding the serum of patients with endometriosis into halogenic stem cells. Most of these cells showed morphological changes that resembled endometrial cells and glands, and this differentiation was more intense and faster, the more significant the severity of endometriosis. In addition, differentiated cells expressed ANXA1. These data reveal that there may be inducing factors in women's blood with endometriosis, highlighting a new theory in endometriosis's pathogenesis. However, further studies are needed to ratify this and help decipher this substance's nature and its molecular composition [37].
