3.2.2. Resolvins

Resolvin D1 (RvD1) Decreases Inflammatory Signs Associated with Endometriosis

The treatment with RvD1 and the analog 17(R)-RvD1 decreased the inflammatory signs of vascular permeability and neurogenic activity as reflected by the significant reduction of Evans Blue dye leakage in ectopic lesions in mice submitted to the experimental model previously mentioned. Moreover, RvD1 effectively reduced vaginal hyperalgesia in mice, proving its potential to relieve abnormal endometriosis-related pelvic pain [41].
