4.1.1. Clinicopathological and Tumor Serum Marker Profile of the Study Cohort

At the time of the diagnosis, the age of the patients ranged between 37 and 76 years old: 22 patients were younger (<55 years old) and 25 patients were older (≥55 years old).

Based on the standards of the FIGO staging, 17 cases were staged as FIGO stage I, 11 cases as FIGO stage II, 18 cases as FIGO stage III, and 1 case FIGO stage IV. According to tumor grade, 13 cases were graded as G1 (well differentiated), 9 cases as G2 (moderately differentiated), and 25 cases as G3 (poorly differentiated or undifferentiated). The distribution of OC histological variants was as follows: LGSC—4 cases; LGEC—5 cases; COC—9 cases; MOC—5 cases; HGSC—8 cases; HGEC—11 cases; undifferentiated—1 case; and mixed tumor (serous, endometrioid, and clear cells phenotypes)—4 cases. According to the pathogenic classification, the cases have been divided in low-grade (type I; 23 cases) and high-grade (type II; 24 cases). The histopathological exam revealed the tumor extension (residual tumor after primary surgery) in 25 cases (residual tumor ≥ 1 cm), with 13 patients diagnosed with a residual tumor < 1 cm and 9 cases without evident data about a residual tumor. Preoperatory CA125 levels higher than 35 U/mL were found in all cases comprised in the study group, ranging between 46–4163 U/mL.
