Reprint
O-GlcNAcylation and Cancer
Edited by
January 2022
112 pages
- ISBN978-3-0365-3083-3 (Hardback)
- ISBN978-3-0365-3082-6 (PDF)
This book is a reprint of the Special Issue O-GlcNAcylation and Cancer that was published in
Biology & Life Sciences
Medicine & Pharmacology
Summary
This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
UNC5A; O-GlcNAcylation; OGT; EZH2; nutrition; epigenetics; colon cancer; transcription; O-GlcNAc; O-GlcNAc transferase; O-GlcNAcase; mOGT; O-GlcNAc; mitochondria; glucose; energy metabolism; breast cancer; O-GlcNAcylation; O-GlcNAc transferase; O-GlcNAcase; cellular stress; cancer; immune surveillance; invasiveness; lung adenocarcinoma; O-GlcNAc transferase; O-GlcNAcylation; SAM68