**Abbreviations**

TCC—terminal complement complex, MAC—membrane attack complex, VEGF—vascular endothelial growth factor, VEGFR—vascular growth factor receptor, ECM—extracellular matrix, SA—sprouting angiogenesis, C5aR1—C5a receptor 1, C3aR—C3a receptor, MMPs—matrix metalloproteinases, MDSC—myeloid-derived suppressor cells, IL—interleukin, INF—interferon, PMX53—C5aR1 inhibitor, HPV—human papilloma virus, TC-1—mouse tumor cell line, RCC—renal cell carcinoma, AMD—age-related macular degeneration, RPE—retinal pigmented epithelium, CNV—choroidal neovascularization, OIR—oxygen-induced retinopathy, and ROP—retinopathy of prematurity.
