*5.2. Bothrops jararaca Venom*

The venom of *B. jararaca* (lot 01/09-2) used in this study was a pool made from the extraction of 697 snakes collected at various Brazilian locations (in the states of São Paulo, Paraná, and Santa Catarina). Extracted venom were pooled and lyophilized at the department of herpetology at Butantan Institute under the coordination of Dr. Marisa Maria Teixeira da Rocha, and assigned for use and testing at the Laboratory of Applied Toxinology at Butantan Institute. The methods and use of venom in this work were approved by Butantan Institute Ethics Committee under the certification CEUAIB #9766150719 (2019).
