*4.6. Dereplication*

MS and MS/MS Data analysis was performed with DataAnalysis 4.4 (Bruker, Billerica, MA, USA). Molecular formula assignment was done manually for all compounds present in the active fractions, allowing a mass accuracy tolerance of ± 2 ppm. Annotation of the MS/MS spectra was performed manually for all the compounds present in active fractions, whenever no hits against our pure compound library were observed. Molecular formula searches were performed on AntiBase 2017 [52], Dictionary of Natural Products [53] and SciFinder® [54].
