*2.4. Physical Characterisation of 3D Printed Carriers*

The 3D printlets are not yet subject to pharmacopoeial requirements; therefore, for the determination of mass uniformity and friability, the tests were performed as described in Chapter 2.9.5 (uniformity of mass of single-dose preparations) and Chapter 2.9.7 (friability of uncoated tablets) of the 9th European Pharmacopoeia for uncoated tablets, with an analytical balance (n = 20; Sartorius LA 230S, Sartorius AG, Göttingen, Germany) and tablet friability apparatus (Erweka AR, Langen, Germany). The printlets' dimension (n = 20; Mitutoyo Absolute, Mitutoyo Corporation, Kawasaki, Japan,) and mechanical strength (n = 10; Erweka TBH 200 TD type, Erweka AR, Langen, Germany). The average values with standard deviation were recorded at each parameter test.
