*Statistical Analysis*

Patient characteristics were expressed as median (and Interquartile range, IQR) and percentage when appropriate. The normality of data distribution was assessed with the Shapiro–Wilk test. To compare the characteristics between groups (i.e., in hospital and out-of-hospital setting), we performed the Mann–Whitney U-test and the Chi-squared test (or Fisher Test when appropriate) for continuous and categorical variables, respectively. A *p*-value < 0.05 was considered statistically significant. To evaluate the variables associated with our primary outcome (i.e., retention in care) we performed logistic regression analysis, including in the multivariable model variables which presented a *p*-value ≤ 0.1 at univariate

analysis. All of the analyses were performed by using IBM SPSS Statistics for (Windows, Version 24.0, Armonk, NY, USA).
