**About the Editor**

#### **Alexandre G. de Brevern**

Alexandre G. de Brevern was trained as a Cell Biologist. He has been a Structural Bioinformatician for nearly 20 years. Senior Researcher at the French National Institute for Health and Medical Research (INSERM), he is the head of team 2 of INSERM UMR S 1134 (Universite´ de Paris and Universite de la R ´ eunion) located in Paris and Saint-Denis de la R ´ eunion (Indian ´ Ocean). He has two main axes of researches: (i) developing innovate methodologies useful for the scientific community and (ii) specific application to proteins implicated in diseases and pathologies. Concerning the first axis, he provided near 20 tools, webservers and databases mainly dealing with the analyses and prediction of protein behaviours. For instance, webservers were made to perform superimposition of protein 3D structures and prediction of protein flexibility. He recently proposed databases dedicated to essential blood group Rhesus and to Calreticuline variants associated to essential thrombocythemia. Concerning the second axis, he used mainly comparative modelling and molecular dynamics to analyse proteins for Red Blood Cells and platelets. We can notice a large number of publications dedicated on the modelling and dynamics of integrins associated to Glanzmann thrombocytopenia or Blood groups. He also extended his work to drug design with collaborations with companies and Next-Generation Sequencing. He had authored more than 150 papers, is editor in six peer-reviewed journals and is implicated in numerous scientific societies and institutes.
