*3.1. Literature Search*

In the 2013 search, one systematic review article was found [9], from which 12 randomized trials were identified among the included studies [26–37]. These were supplemented by 11 randomized trials from an updated literature search in 2017 [38–48] and a further eight randomized studies from the latest updated search in 2020 [49–56].

Thus, the evidence base consists of a total of 31 randomized trials.

A flowchart of included secondary and primary studies is presented in Figure 1; Figure 2, and a list of excluded studies after full-text screening including reasons for their exclusion is presented in Supplementary Material.

**Figure 1.** Flowchart of the search for systematic reviews in 2013.

**Figure 2.** Flowchart of the search for primary studies in 2017 and 2020.
