*Aims*

This Italian C19PRC study uses data collected on a range of demographic, social, and psychological variables from a sample of the general population in Italy. The aim is to describe the effects of the pandemic in adults. Here we provide an overview of the project, and an initial analysis, while additional detailed analyses will require further work. In particular in this paper we focus on anxiety, depression, and stress related to COVID-19 and on the comparison with the same measurements from the first wave of the UK C19PRC study [19,20]. Moreover, comparisons across four Italian regions—selected according to geographic location and infection rate—are provided.

#### **2. Methodological Section**
