3.3.1. Differences in Sex and Age Range

Results of ANOVA analyses showed that WHOQOL global scores differed between male and female participants (*F* (1, 2250) = 9.34, *p* = 0.002), with women reaching lower scores compared to men. No significant differences were found for age range (*F* (2, 2250) = 1.91, *p* = 0.148). About the factor scores of the WHOQOL, two separate MANOVAs were run by taking into account sex and age range as the only between-subject factor. The model where sex was considered showed a significant main effect for this variable (*F* (1, 2250) = 13.51, *p* < 0.001); between-subject tests showed significant differences between men and women in the areas of physical (*F* (1, 2250) = 17.58, *p* < 0.001), psychological (*F* (1, 2250) = 25.85, *p* < 0.001), and environmental (*F* (1, 2250) = 7.00, *p* = 0.008) domains. As can be seen in Table 3, women reported overall worse psychological, physical, and environmental QoL during the pandemic compared to men.

Age range also resulted in a significant between-subject factor for the detection of differences across WHOQOL-BREF domains (*F* (1, 2250) = 11.93, *p* < 0.001). About this, results showed significant differences among groups in the psychological (*F* (2, 2251) = 11.69, *p* < 0.001) and environmental (*F* (2, 2251) = 11.96, *p* < 0.001) domains. Particularly, young adults reported the lowest levels of psychological QoL, which were significantly lower compared to both middle (*p* < 0.001) and older (*p* = 0.019) adults, as attested by Bonferroni's post hoc comparisons. As shown by Table 3, middle adults had the lowest scores at the environment domain compared to both young (*p* < 0.001) and older (*p* = 0.005) adults. No significant differences emerged in both physical (*F* (2, 2251) = 0.39, *p* = 0.675) and social relationship (*F* (2, 2251) = 1.82, *p* = 0.161) domains.
