**Paweł Wa ´nkowicz \*, Aleksandra Szyli ´nska and Iwona Rotter**

Department of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Zolnierska 48, 71-210 Szczecin, Poland; aleksandra.szylinska@gmail.com (A.S.); iwrot@wp.pl (I.R.) ˙ **\*** Correspondence: pawel.wankowicz@pum.edu.pl; Tel.: +48-(91)-4800914

Received: 17 August 2020; Accepted: 3 September 2020; Published: 5 September 2020

**Abstract:** There are considerable psychological and psychiatric consequences of the pandemic. Researchers have started to take into account the real or perceived sense of social threats that may be expressed, such as anxiety, depression, and sleep disorders. However, analyses on pandemic-related anxiety, depression, and sleep disorders mostly rarely addresses the situation of people with autoimmune diseases. Therefore, the aim of this study was to assess the mental health factors among people with systemic lupus erythematosus by quantifying the severity of anxiety, depression, and sleep disorders during the SARS-CoV-2 pandemic. In total, 723 people took part in the study. The study group consisted of 134 individuals with a systemic lupus erythematosus. The control group consisted of 589 people without systemic lupus erythematosus. The regression adjusted by age, gender, and diagnosis of other chronic diseases showed individuals with systemic lupus erythematosus were at a much higher risk of elevated symptoms of anxiety on the GAD-7 scale (OR = 3.683; *p* < 0.001), depression on the PHQ-9 scale (OR = 4.183; *p* < 0.001), and sleep disorders on the Insomnia Severity Index (ISI) scale (OR = 6.781; *p* < 0.001). Therefore, the mental health of patients with systemic lupus erythematosus in the times of the SARS-CoV-2 pandemic is not only an extremely important medical problem but also a social one and must require special attention.

**Keywords:** SARS-CoV-2; COVID-19; SLE; GAD-7; PHQ-9; ISI
