**5. Conclusions**

By applying semi-structured questionnaires, intervention smartphones or online interviews, telerehabilitation has been found to be easier and can address very large communities.

Ongoing weekly activities, in terms of duration, power and endurance, have been found to be declining in the pandemic. In terms of ADLs, these were moderate in frequency and velocity.

Accentuation in cognitive function disorders and emotional status, impaired wellbeing quality of life and sleep and unhealthy eating behaviors have all been observed.

The widespread use of tools capable of assessing and monitoring the degree of motor and cognitive dysfunction has led to the development of new rehabilitation and recovery strategies in terms of changes in the physical and emotional status of healthy adults and patients with neurodegenerative diseases.

For patients with neurodegenerative diseases, the physical activities of aerobic type improved cardiovascular function and the physical performance of the gait pattern.

Specific symptoms, such as remor, rigidity, bradykinesia and postural instability, have been delayed in evolution in the conditions of sustained and correctly performed physical exercises with instructions from online platforms.

The cognitive tools, through their scores, clearly showed an increase in neuropsychiatric symptoms with worsening of depressive symptoms, anxiety and reduced mental wellbeing and speech neurocognitive tasks.

The use of online technology has had a considerable advantage during home confinement due to its ability to remotely monitor the varying degrees of dysfunction in healthy adults and the progression of neurodegenerative diseases.

New health policies that support good mental, physical and quality of life should be supplemented as future perspectives.

In this sense, it is necessary to participate as widely as possible in educational programs developed by specialists, applied to the healthy population, people with special needs and their caregivers, to promote a healthy lifestyle by increasing participation in organized physical activities, increasing socialization, maintaining mental balance and healthy eating behaviors, delivered either directly or through the participation of online technology.

It is necessary for state governments to be involved and to create new policies for training caregivers with financial support for new recovery and rehabilitation strategies. Thus, it will be possible to increase the access for other categories of staff who can be easily trained and understand the techniques of care at home or in assisted communities.

The importance of an interdisciplinary strategy that includes the promotion of physical activity and encouraging use of technology for PA participation should be stressed.

#### *Limitations and Advantages of the Study*

The limitations of this study include that the possible subjective nature of the information presented and the relatively small number of the studies that satisfied our selection criteria.

The advantages of this study include its approach to complex issues on the impact of the COVID-19 pandemic lockdown for both healthy people and neurodegenerative patients. The study provides new information based on the literature research, which could be used for the creation of new health policies and future perspectives.

**Author Contributions:** M.B.: conceptualization, literature selection and analysis; M.D.: data collection and quality assessment of papers; L.R.: methodology and discus; M.M.: research strategy, literature selection, figures and tables; M.R.R.: translation. All authors have equal contributions to the published version of the manuscript. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research received no external funding.

**Institutional Review Board Statement:** Ethical approval number 25/10.10.2021.

**Informed Consent Statement:** Not applicable.

**Data Availability Statement:** Not applicable.

**Conflicts of Interest:** The authors declare no conflict of interest.
