**5. Conclusions**

Polish MS patients surveyed during the first stage of the COVID-19 pandemic presented with a moderate to high level of perceived stress and preferred problem-focused coping strategies. The burden of the pandemic perceived by the patients was associated mainly with their social functioning and, to a lesser degree, with health status or health care services. The level of stress and coping profile showed more relationships with pandemic impact upon social issues than with disease-related variables. Consequences of the pandemic should be addressed with adequate support and counseling in management of MS patients.

**Supplementary Materials:** The following are available online at https://www.mdpi.com/article/10 .3390/jcm10184215/s1, Supplementary Materials: Covid MS questionnaire.

**Author Contributions:** Conceptualization, A.P.-D., J.R. and S.B.; Methodology, A.P.-D., M.P. and A.R.-M.; Software, M.P. and T.P.; Validation, M.P. and A.R.-M.; Formal Analysis, A.R.-M., J.C.-Ł. and M.P.; Investigation, A.P.-D., J.C.-Ł., E.G. and M.P.; Resources, J.C.-Ł. and E.G.; Data Curation, A.P.-D. and T.P.; Writing—Original Draft Preparation, A.P.-D. and J.C.-Ł.; Writing—Review and Editing, J.R. and T.P.; Visualization, J.C.-Ł.; Supervision, S.B. and J.R.; Project Administration, A.P.-D.; Funding Acquisition, A.P.-D. and S.B. All authors have read and agreed to the published version of the manuscript.

**Funding:** The study was supported with Wroclaw Medical University grant SUB.C 220.21.088.

**Institutional Review Board Statement:** The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of Wroclaw Medical University (Ref. No KB-417/2020).

**Informed Consent Statement:** Informed consent was obtained from all subjects involved in the study.

**Data Availability Statement:** The data presented in this study are available on request from the corresponding author.

**Conflicts of Interest:** The authors declare no conflict of interest.
