**Preface to "***Clostridioides difficile* **Infection"**

This book collects multidisciplinary research articles focused on *Clostridioides difficile* infection. The contributions collected here shed some light on grey areas of our knowledge of *Clostridioides difficile*, including regional *Clostridioides difficile* phenotypic and genotypic patterns, the *Clostridioides difficile* infection clinical course and the mortality rate in different settings and patient case-mix, the levels of *Clostridioides difficile* toxins in patients' sera, and novel, promising therapeutic approaches. This collection serves as a valuable reservoir of knowledge for scientists and researchers in the field of infectious diseases.

I would like to thank the scientific community who showed interest in and submitted manuscripts to this collection. I am grateful to the Editor-in-Chief of *Antibiotics*, Professor Nicholas Dixon, and to the Managing Editor, Ms. Monica He, for her unvaluable support. Special thanks go to my mentor, Professor Nicola Petrosillo, who introduced and always supported me in my career and research interests, and to my beloved family, Patricia and Meletta-Flaminia.

> **Guido Granata** *Editor*
