*4.4. Binding Pockets*

Residues corresponding to the binding pocket of ABCG2 for imatinib, mitoxantrone and SN38 were identified by taking residues with any part 5 Å from the substrate in structures 6VXH, 6VXI, and 6VXJ, respectively. Residues contributing to potential binding pockets for cholesterol in ABCG5/G8 were taken from Lee et al. 2016 [9]. The columns corresponding to these residues were identified and compared.
