*2.12. ABCA7*

The length of the ABCA7-201 transcript is 6815 bp and it has 47 exons. The 5′UTR spans 227 nt with one annotated intron-intron 1-2 (1028 bp). One sub-region (−137 to −73) shows the highest level of conservation. One uATG (−103), which is conserved in placental mammals (cat. 3) and has an adequate context and middle TIS score, was found. One uORF overlapping with the main ORF was predicted to start from this uATG. One probable RG4-forming sequence was placed to −217 to −158. Three stem loops were predicted in this region. The ABCA7 protein was found to be expressed in many human tissues (29/45). The mode expression score was low, enhanced only in bone marrow and spleen.
