*2.10. ABCA9*

The human *ABCA9* gene has no known orthologs in Sauropsida (reptiles and birds) and ray-finned fishes. The ABCA9-201 transcript is 6377 bp long and has 39 exons. One 9726 bp long intron (Intron 1-2) is annotated within the 75 nt long 5′UTR. Two sub-regions fulfilled the criteria for the most conserved ones. Three uATGs (1. −70, 2. −58, 3. −54) were found; the first and third are conserved within placental mammals (cat. 3) and second only within primates (cat. 1). The first and second show adequate context and third weak context; however, all have low TIS scores. Two uORFs (1. −70, 2. −54) were described, the first 33 and second 39 nt long. No probable RG4-forming sequence was detected and two stem loops were predicted in this region. The ABCA9 protein was found to be expressed in all human tissues (45). The mode expression score was high.
