*3.12. Miscellanea*

Finally, minocycline [69], ibuprofen [70], indomethacin [71], phosphodiesterase-5 inhibitors (i.e., sildenafil) [72], benzodiazepine inverse agonists [73], AST-120 [74], a microspherical carbon with a selective adsorbent profile for small molecules such as ammonia, and liposome-supported peritoneal dialysis [75] are all being tested in animal models and/or early phase clinical studies. For some, anecdotal, direct clinical experience is also available, especially where the tested drug has alternative indications.
