*Article* **Nutritional Influences on Locomotive Syndrome**

**Sadayuki Ito 1, Hiroaki Nakashima 1,\*, Kei Ando 1, Masaaki Machino 1, Taisuke Seki 1, Shinya Ishizuka 1, Yasuhiko Takegami 1, Kenji Wakai 2, Yukiharu Hasegawa 3 and Shiro Imagama 1**


**Abstract:** Healthy dietary habits are important to prevent locomotive syndrome (LS). We investigated the relationship between LS and nutritional intake using community health checkup data. We included 368 participants who underwent LS staging, blood sampling, and nutritional intake assessments. Participants (163 adults < 65: 205 older adults ≥ 65) were divided into normal (N; LS stage 0) and LS (L; LS stage 1–2) groups, and blood sample data and nutritional intake were compared between groups. Among adults (N group, 71; L group, 92), low-density lipoprotein cholesterol (LDL-C) was significantly lower, and Vitamin B1 intake was significantly higher in the L than in the N group; LDL-C, *p* = 0.033; Vitamin B1, 0.029. Among older adults (N group, 85; L group, 120), hemoglobin (Hb), albumin, and calcium levels were significantly lower, and sodium, monounsaturated fatty acids (MUFA), and n-6 polyunsaturated fatty acids (n-6 PUFA) were significantly higher in the L than the N group; Hb, *p* = 0.036; albumin, 0.030; calcium, 0.025; sodium; 0.029; MUFA; 0.047, n-6 PUFA; 0.0233). Logistic regression analysis indicated that sodium was the risk factor for the L group (exp (B) 1.001, 95% CI: 1–1.001, *p* = 0.032). In conclusion, salt intake was associated with LS.

**Keywords:** locomotive syndrome; nutrition; health checkup data
