**An Evolutionary and Environmental Perspective of the Interaction of Nanomaterials with the Immune System-The Outcomes of the EU Project PANDORA**

Editor

**Diana Boraschi**

MDPI • Basel • Beijing • Wuhan • Barcelona • Belgrade • Manchester • Tokyo • Cluj • Tianjin

*Editor* Diana Boraschi National Research Council Italy

*Editorial Office* MDPI St. Alban-Anlage 66 4052 Basel, Switzerland

This is a reprint of articles from the Special Issue published online in the open access journal *Nanomaterials* (ISSN 2079-4991) (available at: https://www.mdpi.com/journal/nanomaterials/ special issues/Immune PANDORA).

For citation purposes, cite each article independently as indicated on the article page online and as indicated below:

LastName, A.A.; LastName, B.B.; LastName, C.C. Article Title. *Journal Name* **Year**, *Volume Number*, Page Range.

**ISBN 978-3-0365-3947-8 (Hbk) ISBN 978-3-0365-3948-5 (PDF)**

Cover image courtesy of Diana Boraschi

SEM image of human monocytes in a collagen matrix; from Imaging Facility of Stazione Zoologica Anton Dohrn, Napoli, Italy.

© 2022 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications.

The book as a whole is distributed by MDPI under the terms and conditions of the Creative Commons license CC BY-NC-ND.

## **Contents**


Reprinted from: *Nanomaterials* **2020**, *10*, 1337, doi:10.3390/nano10071337 .............. **115**

#### **Rujiu Hu, Haojing Liu, Mimi Wang, Jing Li, Hua Lin, Mingyue Liang, Yupeng Gao and Mingming Yang**


#### **Mayra M. Ferrari Barbosa, Alex Issamu Kanno, Leonardo Paiva Farias, Mariusz Madej, Gerg ¨o Sipos, Silverio Sbrana, Luigina Romani, Diana Boraschi, Luciana C. C. Leite and Paola Italiani**

Primary and Memory Response of Human Monocytes to Vaccines: Role of Nanoparticulate Antigens in Inducing Innate Memory

Reprinted from: *Nanomaterials* **2021**, *11*, 931, doi:10.3390/nano11040931 ............... **157**

### **Benjamin J. Swartzwelter, Craig Mayall, Andi Alijagic, Francesco Barbero, Eleonora Ferrari, Szabolcs Hernadi, Sara Michelini, Natividad Isabel Navarro Pacheco, Alessandra Prinelli, Elmer Swart and Manon Auguste**

Cross-Species Comparisons of Nanoparticle Interactions with Innate Immune Systems: A Methodological Review

Reprinted from: *Nanomaterials* **2021**, *11*, 1528, doi:10.3390/nano11061528 .............. **173**

## **About the Editor**

**Diana Boraschi** is an immunologist who built her experience in academic institutions and industrial settings in her home country (Italy) and abroad. She is Senior Associate Researcher at the Italian National Research Council and at the Stazione Zoologica Anton Dohrn in Napoli, Italy. She is currently serving as Director of the Center of Immunology and Biomaterials at the Shenzhen Institute of Advanced Technologies (SIAT) of the Chinese Academy of Sciences and as Distinguished Professor at the Department of Pharmacology SIAT in Shenzhen, China. She is the author of over 200 research articles in immunology (h-index 62, over 13500 citations). She is closely involved in higher education training activities in Europe, Asia, Africa, and South America, with a focus on poverty-related diseases. In 2017, she received an honorary PhD degree from the University of Salzburg (Austria). Her area of expertise is innate immunity and inflammation, with a particular focus on macrophages and cytokines of the IL-1 superfamily and the interaction of engineered nanomaterials with immunity in humans and environmental species.
