**About the Editors**

### **Mary J. Meegan**

Professor Mary J Meegan completed her PhD degree in University College Dublin under the direction of Professor Dervilla Donnelly in the area of natural product chemistry and subsequently carried out postdoctoral research at the University Chemical Laboratory, Cambridge University, in the research group of Professor Alan Battersby in the area of porphyrin synthesis and biosynthesis. Following further research periods at University College Dublin and CNRS Gif-sur-Yvette, she was appointed as a lecturer in Pharmaceutical Chemistry at the School of Pharmacy and Pharmaceutical Sciences in Trinity College Dublin. Her research experience is in the general area of pharmaceutical and medicinal chemistry, with over 100 peer-reviewed scientific papers covering topics such as: (i) novel ligands for nuclear receptors (ER&AR), HSP90 and tubulin; (ii) the synthesis of small-molecule inhibitors of the enzymes involved in the metastasis of breast tumors; (iii) the design and evaluation of dual targeting agents for tubulin and aromatase; and (iv) the design of drugs which target the proliferation of chronic lymphocytic leukaemia (CLL), Burkitt lymphoma and related malignancies. Research collaborations are established within Trinity College with Dr. Niamh O'Boyle (School of Pharmacy and Pharmaceutical Sciences), Dr D Zisterer, Dr D Fayne in the School of Biochemistry and Immunology and also with many European research centers. She is a member of the Royal Society of Chemistry and the Irish and European Associations for Cancer Research.

### **Niamh M O'Boyle**

Dr. Niamh O'Boyle is an Assistant Professor in Pharmaceutical Chemistry in Trinity College Dublin. She received her BSc (Pharm) (1st class) and PhD degrees from Trinity College Dublin, working with Prof. Mary J. Meegan. She subsequently completed postdoctoral fellowships at the University of Gothenburg (Sweden) with Prof. Ann-Therese Karlberg and the School of Biochemistry and Immunology (TCD), working with Prof. Daniela Zisterer. Niamh is fascinated by the interaction of chemicals, both drugs and toxins, with the body. This inspires her research in the development of novel drugs for hard-to-treat cancers and in discovering the underlying mechanisms of skin allergy. Drug targets of interest include the protein tubulin, the estrogen and progesterone receptors, and the role of reactive oxygen species.

Niamh is a member of the Pharmaceutical Society of Ireland, the Royal Society of Chemistry and the Irish and European Associations for Cancer Research. She is the early career representative on the Royal Society of Chemistry Ireland Regional Steering Group (2020–2023) and is a committee member of the international GP2A medicinal chemistry group. She has been appointed to the Physical, Chemical & Mathematical Sciences multidisciplinary committee of the Royal Irish Academy (2022-2026). She is involved in the CRYSTAL3 EU MSCA-Rise project and the COST action CA17104 STRATAGEM "New diagnostic and therapeutic tools against multidrug resistant tumours".
