*2.2. Intracerebroventricular Cannulation*

A stainless steel Luer cannula (10 mm long) was implanted in the right lateral cerebral ventricle for icv. administration. The cannula was inserted under sodium pentobarbital (Euthasol, Phylaxia-Sanofi, 35 mg/kg, ip.) anaesthesia, according to the following stereotaxic coordinates: 0.2 mm posterior and 1.7 mm lateral to the bregma, and 3.7 mm deep from the dural surface [37]. Subsequently, it was secured to the skull with dental cement and acrylate. The experiments started after a recovery period of 1 week. All experiments were carried out between 8:00 a.m. and 10:00 a.m.
