*3.6. Publication Bias*

Publication bias was examined through funnel plots and statistically using the Trim and Fill method (results not shown). Publication bias evaluation was performed separately considering the 3 scales used to measure the effects of psilocybin in depression, through BDI and anxiety, through STAI. Funnel plots indicate asymmetries in the distribution of studies based on sample sizes. The presence of publication bias was further explored using Egger's regression test. This test indicates evidence of publication bias for the effects of psilocybin on depression and anxiety (*p*-value > 0.05).
