3.1.1. Elevated Plus Maze

The 0.1 μg dose of Kp-8 significantly reduced the percentage of entries into the open arms of the plus maze (Figure 1a, F (2, 20) = 9.196, *p* = 0.0007), as well as the percentage of time spent in the open arms of the maze (Figure 1b, F (2, 20) = 4.431, *p* = 0.0202). A decrease in the total number of entries into the arms was induced by both 0.1 μg and 1 μg of Kp-8 (Figure 1c, F (2, 20) = 5.927, *p* = 0.0153). There was no significant difference among the groups in the total time spent in the arms (Figure 1d, F (2, 20) = 1.932, *p* = 0.1710).
