*4.2. 8-OHdG*

When DNA is exposed to ROS, compounds such as 8-hydroxy guanine, 8-OHdG, and MDA-DNA are formed to break the DNA strands. 8-OHdG is composed of guanine oxidation, which plays an important role in mutagenic DNA damage and is used as a suitable indicator of oxidative damage to DNA [42].
