*2.11. Statistical Analysis*

Data were analyzed using the statistical software SPSS 22.0 (SPSS, Chicago, IL USA), and continuous data are expressed as the means ± SEM. Nonparametric results were examined by the Mann–Whitney U test and Wilcoxon signed ranked test. Parametric results were tested by two-way repeated-measures ANOVA (group × time points) and the Newman–Keuls post hoc test to identify significant changes pre- vs. postintervention and pre- vs. post-graded exercise tests. Correlations were measured by Pearson's correlation coefficient. The level of statistical significance was *p* < 0.05.
