**6. Conclusions**

pCDs have many advantages, including a sustainable source of raw materials, low cost, multiple synthetic methods, and a simple synthesis procedure. They not only have the characteristics of cyclodextrin molecules, such as an internal hydrophobic-external hydrophilic cavity structure and hand-shaped features, but they also have the excellent mechanical strength, hardness, and good thermal stability of polymers.

This article introduced the research progress of pCDs, including their synthesis and applications in analytical separation science, materials science, and biomedicine. The field of analysis and separation science mainly uses the cavity structure and hand shape characteristics of pCDs to realize separation and detection. In the field of materials science, CDs have been incorporated into various materials. Compared with traditional materials, pCDs have the characteristics of a high flux and solubility, resulting in practical materials with superior properties. In the field of biomedicine, compared with traditional materials, pCDs have the advantages of specific identification, non-toxicity, and good biocompatibility. In short, pCDs have been increasingly applied in the fields of analysis and separation science, material science, and biomedicine because of their unique characteristics.

While emphasizing the multi-field applications of pCDs, this article focused on its scientific and technological innovation as drug delivery vehicles, using the latest research as examples to illustrate their potential for cancer treatment and the elimination of fungi. A summary of the development trend in pCDs from multiple fields and perspectives illustrates the large growth in the amount of pCD research and the large potential for development, and this work provides direction for future research.

**Author Contributions:** Literature search, Y.L. and T.L.; figures, Q.W., Y.L. and S.L.; study design, C.C. and X.H.; data collection, C.L. and Q.W.; data analysis, X.H. and C.L.; data interpretation, T.L. and S.L.; writing, C.C. and Y.L. All authors have read and agreed to the published version of the manuscript.

**Funding:** This work was supported by National Natural Science Foundation of China (81901896); and Scientific Research Foundation of Fuzhou University (GXRC-19025).

**Data Availability Statement:** Data are available in a publicly accessible repository.

**Conflicts of Interest:** The authors declare no conflict of interest.
