The Effect of Palmitate

The treatment of patient's myoblasts with palmitate for 16 h prior to measurement led to a significant reduction of BR, SRC, and ATP-R values compared to the values without FAs. In contrast, controls showed similar BR, MR, SRC, and ATP-R values to those without FAs after treatment with palmitate (Figure 1, Table 3).

**Table 3.** The effect of treatment of patients (*n* = 5) and controls (*n* = 5) myoblasts with 300 µM palmitate or oleate conjugated with BSA on key parameters for mitochondrial function (basal, MR, ATP production and SRC). Significant differences between values obtained with or without FAs are presented if *p* ≤ 0.05. *p*.: *p*-values, –FAs: without Fatty acids, Pa: palmitate. O: oleate.

