Diagnosis

Patients with clinical symptoms are advised to undergo direct immunofluorescence (DIF) tests on perilesional skin. If the test result is negative, new material is collected, and it is determined whether the patient is on a GFD, which could lead to false-negative results [157]. Other confirmatory tests such as the dosage of anti-tTG can be used in patients with symptoms suggesting DH but with negative direct immunofluorescence [158].
