Treatment

Following a rigorous GFD should be the treatment to GA patients. Moreover, studies show that immunotherapy with steroid and intravenous immunoglobulins (IVIG) can be an efficient treatment for such patients [152].

### 3.2.2. Dermatitis Herpetiformis

Dermatitis herpetiformis (DH), repeatedly associated with CD, is an autoimmune, chronic, and recurrent cutaneous-intestinal disorder detected in genetically susceptible individuals [11,153,154]. Anti-tTG antibodies that also recognize epidermal transglutaminase (ETG) can be produced after exposure to gluten. ETG is homologous to tTG in terms of structure and is the primary antigen in DH [153]. IgA antibody deposition in dermal papillae causes pruritic, vesiculobullous, and localized lesions in DH patients. DH affects the extensor surfaces such as knees, buttocks, elbows, and scapular areas [153,155,156].
