3.2.1. Design

Thirty-two articles were included in this study (Table 3). Eighteen articles [16–33] evaluated the clinical outcome of regenerative endodontic procedures (REP) and five articles [34–38] on the apexification procedure. Only nine articles [39–47] evaluated and compared the clinical outcome between regeneration and apexification procedure.


**Table 3.** Data extraction from included studies – the clinical protocol.









concentrated platelet-rich plasma; PPP = platelet-poor plasma; PRF = platelet-rich fibrin; CEJ = cementoenamel junction; MTA = mineral trioxide aggregate;

hDPSC = human dental pulp stem cells.
