**Preface to "Surface Plasmon Resonance for Biosensing"**

Point-of-care (POC) methods for medical screening and timely disease diagnosis allow for a continuous general health state assessment and are central for the future development of health systems. From this point of view, biosensors based on surface plasmon resonance (SPR) effects can play a major role because of their high sensitivity, reduced fabrication process complexity, and high level of integration. They offer the potential to move proteomic biology into the clinical setting as a routine diagnostic procedure and surpass the technical challenges of conventional methods. The light-generated SPR phenomena depend on the fine-tuning of the wavelength against the geometry of the resonant structures and the optical properties of the materials that are used. Targeting the optimization of this key point, a large panorama of different structure configurations can be proposed, based on different schemes for plasmon generation and sensor interrogation methods, ranging from local nanoparticle response (LSPR), optical waveguides, optical fibres, and interferometers, to advanced structures where the SPR is enhanced by the mutual influence of different nanostructures with 2D materials. The overall performance of the resulting biosensor depends on the ability to immobilize specific antibodies while maintaining their biological activity, as well as providing antibodies accessibility to the analyte. Surface Plasmon Resonance for Biosensing is a very interdisciplinary research topic and this book addresses the recent research results in this exciting area by proposing multiple perspectives related to this topic, ranging from material science to biochemistry, nanotechnology, and low-power electronic systems.

> **Alessandro Fantoni** *Editor*
