*1.1. Incidence of Thyroid Cancer*

Thyroid cancer is the most common endocrine tumor in the general population and the incidence continues to rise in the United States [1]. The American Cancer Society estimates that there will be 44,280 new cases of thyroid cancer (12,150 in men and 32,130 in women) and about 2200 deaths (1050 in men and 1150 in women) in the United States in 2021 [2]. The increased incidence could be possibly attributed to the increased detection of

**Citation:** Pitsava, G.; Stratakis, C.A.; Faucz, F.R. *PRKAR1A* and Thyroid Tumors. *Cancers* **2021**, *13*, 3834. https://doi.org/10.3390/cancers 13153834

Academic Editors: Fabio Medas and Pier Francesco Alesina

Received: 16 June 2021 Accepted: 27 July 2021 Published: 30 July 2021

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these tumors with imaging technics (like ultrasound and computed tomography (CT)) that better characterize incidental findings of small thyroid nodules [3].
