*3.7. Univariate and Multivariate Analysis for PFS and OS*

At univariate Cox-regression analysis, serum albumin level [HR 0.408 (95% CI 0.168–0.991), *p* = 0.048], total lymphocyte count [HR 0.999 (95% CI 0.999–1.00), *p* = 0.035], and baseline CONUT score [HR 12.211 (95% CI 4.084–36.512), *p* < 0.0001] were prognostic factors for PFS as well as serum albumin level [HR 0.224 (95% CI 0.083–0.604), *p* = 0.003], serum total cholesterol [HR 0.982 (95% CI 0.969–0.995), *p* = 0.007], and CONUT score [HR 23.551 (95% CI 4.949–112.060), *p* < 0.0001] were prognostic factors for OS. According to stepwise Cox-regression analysis, the CONUT score was the only independent prognostic factor associated with PFS (*p* < 0.0001) and OS (*p* < 0.0001), whose HRs were confirmed to be 12.211 (95% CI 4.084–36.512) for PFS and 23.551 (95% CI 4.949–112.060) for OS.
