5.1.2. PTC Tissue-Targeting Probes

Zhong et al. generated a PTC tissue-specific aptamer (TC-6) via tissue-based systematic evolution of ligands by exponential enrichment (SELEX), with clinical PTC tissues (positive control) and non-tumor thyroid tissues (negative control). The TC-6 can specifically distinguish PTC from other non-tumor tissues (Figure 14), and suppress the migration and invasion of PTC cells [16]. However, the exact molecular target remains unknown.
