**5. Patents**

The preparation of grape canes before extraction in the pilot plant followed the procedure described in the Patent [13]. The formulation of the microparticles of phenolic compounds from the extract of grape canes of *V. vinifera* and the application of HP-*β*-CD to form the IC and the use of MD as a coating agent are described in the Patent [17].

**Supplementary Materials:** The following are available online at https://www.mdpi.com/article/10 .3390/antiox10071130/s1, Table S1: Identification and quantification of phenolic compounds from GCPPE using LC-ESI-LTQ-Orbitrap-MS in negative mode.

**Author Contributions:** Conceptualization, D.E.-A., C.G.-G., C.M., J.L., D.v.B. and A.V.-Q.; methodology, D.E.-A., J.A.-G., J.S., J.L.-C., C.G.-G., J. L and A.V.-Q.; validation, A.V.-Q. and C.G.-G.; formal analysis, D.E.-A., J.A.-G., J.L.-C. and J.S.; investigation, D.E.-A., J.A.-G. and J.S.; resources, A.V.-Q., C.G.-G., R.M.L.- R., C.M., J.L. and D.v.B.; data curation, D.E.-A., J.A.-G. and J.S.; writing—original draft preparation, D.E.-A.; writing—review and editing, D.E.-A., A.V.-Q., C.G.-G., C.M., J.A.-G., D.v.B., R.M.L.-R. and J.S.; visualization, D.E.-A.; supervision, A.V.-Q., C.G.-G., R.M.L.-R. and C.M.; project administration, D.E.-A., A.V.-Q., C.G.-G., C.M. and R.M.L.-R.; funding acquisition, D.E.-A., C.M., A.V.-Q. and R.M.L.-R. All authors have read and agreed to the published version of the manuscript.

**Funding:** This research was supported by the Agencia Nacional de Investigación y Desarrollo (ANID)/PCI-REDES170051; ANID PIA/APOYO CCTE AFB170007; CORFO 14 IDL2- 30156, from Chile; CICYT [AGL2016-75329-R], CIBEROBN from the Instituto de Salud Carlos III, ISCIII from the Ministerio de Ciencia, Innovación y Universidades, (AEI/FEDER, UE) and Generalitat de Catalunya (GC) [2017SGR 196]. Danilo Escobar-Avello is grateful to ANID/Scholarship Program/DOCTORADO BECAS CHILE/2017—72180476. Javier Avendaño-Godoy is grateful to ANID/Scholarship Program/DOCTORADO NACIONAL/2020-21202096. Anna Vallverdú-Queralt thanks to the Ministry of Science, Innovation and Universities for the Ramon y Cajal contract (RYC-2016-19355).

**Institutional Review Board Statement:** Not applicable.

**Informed Consent Statement:** Not applicable.

**Data Availability Statement:** Data is contained within the article and Supplementary Materials.

**Acknowledgments:** The authors would like to thank the CCiT-UB for the mass spectrometry equipment and to Yamil Neira from Viña de Neira, who provided the grape cane samples.

**Conflicts of Interest:** Rosa M. Lamuela-Raventós reports receiving lecture fees from Cerveceros de España and Wine in moderation. She also received lecture fees and travel support from Adventia. The other authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
