*Article* **Morphometric Maps of Bilateral Asymmetry in the Human Humerus: An Implementation in the R Package Morphomap**

**Antonio Profico 1,\*,†, Carlotta Zeppilli 2,\*,†, Ileana Micarelli 2, Alessandro Mondanaro 3, Pasquale Raia 4, Damiano Marchi 5,6, Giorgio Manzi 2 and Paul O'Higgins 1,7**


**Abstract:** In biological anthropology, parameters relating to cross-sectional geometry are calculated in paired long bones to evaluate the degree of lateralization of anatomy and, by inference, function. Here, we describe a novel approach, newly added to the morphomap R package, to assess the lateralization of the distribution of cortical bone along the entire diaphysis. The sample comprises paired long bones belonging to 51 individuals (10 females and 41 males) from The New Mexico Decedent Image Database with known biological profile, occupational and loading histories. Both males and females show a pattern of right lateralization. In addition, males are more lateralized than females, whereas there is not a significant association between lateralization with occupation and loading history. Body weight, height and long-bone length are the major factors driving the emergence of asymmetry in the humerus, while interestingly, the degree of lateralization decreases in the oldest individuals.

**Keywords:** biological anthropology; biomechanics; cortical thickness; lateralization; modern humans; NMDID; upper limb
