*3.4. Secondary Outcome (Daily Life Activity, UPDRS-II): PMA*

In PMA of daily life activity evaluated by UPDRS-II, statistical significance was shown between the following comparisons presented with MD and 95% CI **(in favor of bold marks):** (1) **ELEC** vs. CONV (MD −4.50, 95% CI −6.19 to −2.80); (2) **MANU** vs. CONV (MD −4.07, 95% CI −4.87 to −3.27). In other comparisons, such as BEEV vs. CONV, ELEC vs. SHAM, and MANU vs. SHAM, the acupuncture modality showed a tendency to be more effective than the control group, but this was not statistically significant. Detailed descriptions of the effect size and each trial-based forest plot are provided in Supplementary Materials Digital Content 4.
