*2.1. Search Strategy*

Eligible studies were systematically searched from their inception to June 2021 using Medline (via PubMed), Cochrane Library, Embase (via Elsevier), China National Knowledge Infrastructure, Korea Citation Index (KCI), NDSL, Research Information Sharing Service, and Oriental Medicine Advanced Searching Integrated System. A mixture of free words and medical subject headings were used for PD and acupuncture. There were no language restrictions. The search strategy in Medline (via PubMed) is as follows: #1 parkinson disease [Mesh] OR parkinson disease OR Idiopathic Parkinson's Disease OR Lewy Body Parkinson's Disease OR Parkinson's Disease, Idiopathic OR Parkinson's Disease, Lewy Body OR Parkinson Disease, Idiopathic OR Parkinson's Disease OR Idiopathic Parkinson Disease OR Lewy Body Parkinson Disease OR Primary Parkinsonism OR Parkinsonism, Primary OR Paralysis Agitans.

#2 acupuncture [Mesh] OR Acupuncture OR Pharmacopuncture OR Acupuncture Treatment OR Acupuncture Treatments OR Treatment, Acupuncture OR Therapy, Acupuncture OR Pharmacoacupuncture Treatment OR Treatment, Pharmacoacupuncture OR Pharmacoacupuncture Therapy OR Therapy, Pharmacoacupuncture OR Acupotomy OR Acupotomies OR Electroacupuncture OR Bee Venoms OR Venoms, Bee OR Bee Venom OR Venom, Bee OR Apis Venoms OR Venoms, Apis OR Apitoxin OR Honeybee Venoms OR Venoms, Honeybee OR Honeybee Venom OR Venom, Honeybee OR Fire needle therapy OR Fire acupuncture.

#3 #1 AND #2: A detailed explanation of the search terms used in each database is provided in Supplementary Materials Digital Content 1.
