*2.5. Risk of Bias Assessment*

The risk of bias of the included studies was assessed according to the Cochrane Handbook version 5.1.0. assessment tool by two independent researchers (CYK and BL) [15]. In the Cochrane's risk of bias tool, domains for random sequence generation, allocation concealment, blinding of participants and personnel, blinding of outcome assessment, incomplete outcome data, selective reporting, and other sources of bias are evaluated as "low," "high," or "unclear" [15]. The risk of bias summary figure was produced using the RevMan Software version 5.4 (The Cochrane Collaboration, London, England). Discrepancies were resolved by discussion with a third researcher (KIK).
