*2.4. Risk of Bias Assessment*

Two independent researchers (J.L., M.K.) used the Cochrane risk of bias assessment tool to evaluate the quality of the research methods of the included studies [26]. Random sequence generation; allocation concealment; blinding of participants, personnel, and outcome assessors; incomplete outcome data; selective outcome reporting; and other sources of bias were graded as low, unclear, and high. Disagreement between the two researchers was resolved by discussion with a third independent reviewer (M.J.). Review Manager (RevMan) version 5.4 software was used to illustrate the risk of bias.
