*2.3. Assessment of Risk of Bias in Individual Studies*

Two independent reviewers (JJCA and VFM) were in charge of the assessment of the risk of bias of each article using the items of the Review Manager (RevMan) tool (Review Manager (RevMan) [Computer program]. Version 5.4, The Cochrane Collaboration, 2020): randomization sequence, allocation concealment, blinding of participants, blinding of assessment, attrition bias, and information bias. The risk of bias of each one of these items was determined by the following premises:


