*Article* **Internal Migration Experience and Depressive Symptoms among Middle-Aged and Older Adults: Evidence from China**

**Xiaodong Zheng 1,\* , Yue Zhang <sup>1</sup> , Yu Chen <sup>2</sup> and Xiangming Fang 3,4**


**Abstract:** Background: This study aimed to examine the association of internal migration experience with depressive symptoms among middle-aged and elderly Chinese, as well as explore possible mechanisms of the relationship. Methods: Participants were from the China Health and Retirement Longitudinal Study (CHARLS), a nationally representative sample of residents aged 45 years and older (*n* = 43,854). Survey data on depressive symptoms and internal migration experience were collected from biennial CHARLS surveys (CHARLS 2011/2013/2015) and a unique CHARLS life history survey in 2014, respectively. Multiple logistic regressions and the Karlson–Holm–Breen (KHB) method were employed in the statistical analyses. Results: The overall prevalence rate of depressive symptoms among middle-aged and older adults was 34.6%. Internal migration experience was associated with higher risks of depressive symptoms (OR = 1.07, 95% CI = 1.02–1.12, *p* < 0.01), especially among females (OR = 1.08, 95% CI = 1.01–1.14, *p* < 0.05), middle-aged adults (OR = 1.12, 95% CI = 1.06–1.19, *p* < 0.001), rural-to-urban migrants who had not obtained an urban *hukou* (OR = 1.13, 95% CI = 1.07–1.19, *p* < 0.001), and those who had low migration frequency and first migrated out at 35 years of age or older. Chronic disease (17.98%, *p* < 0.001), physical injury (7.04%, *p* < 0.001), medical expenditure (7.98%, *p* < 0.001), pension insurance (4.91%, *p* < 0.001), and parent–child interaction (4.45%, *p* < 0.01) were shown to mediate the association of internal migration experience with depressive symptoms. Conclusions: This study indicates that there is a significant association between internal migration experience and high risks of depression onset later in life. It is suggested to reduce institutional barriers for migrants and implement evidence-based interventions to improve migrants' mental health.

**Keywords:** depressive symptoms; internal migration experience; middle-aged; elderly; China
