3.1.8. Azaphilones from *Pleosporales* Genus

The marine-derived fungus *Pleosporales* sp. CF09–1 produced the uncommon bisazaphilones dipleosporalones A and B (**89–90**) (Figure 8) [57]. These compounds own a 6/4/6 ring system that might come from a [2 + 2] cycloaddition reaction between two pinophilin B-type monomers and represents the first example of this coupling.

**Figure 8.** Chemical structures of azaphilones from *Pleosporales*: **89–90**: pleosporales A and B [57].
