3.1.7. Azaphilones from *Phomopsis* Genus

Culture of the endophyte fungus *Phomopsis* sp. CGMCC No.5416 yielded the three azaphilones phomopsones A–C (**81–83**), presenting anti-HIV and cytotoxic activity [55]. From

the deep-sea-derived fungus *Phomopsis tersa* FS441, five chlorinated azaphilones named tersaphilones A–E (**84–88**) presenting unique structures were isolated [56] (Figure 7).

**Figure 7.** Chemical structures of azaphilones from *Phomopsis*: **81–83**: phomopsones A–C; **84–88**: tersaphilones A–E [55,56].
