**4. Conclusions**

The present study led to the isolation of eight cytotoxic and antimicrobial compounds, seven of which turned out to be new to science. Therefore, the potential of Sordariomycetes as prolific producers of bioactive secondary metabolites was again demonstrated here. Moreover, the production of these compounds by *Jugulospora vestita* and other strains belonging to the same genus, but not by other related genera of Sordariales, suggests that the production of secondary metabolites could be suitable as chemotaxonomic markers.

**Supplementary Materials:** The following are available online at http://www.mdpi.com/2309-608X/6/4/188/s1, Figure S1: 1H NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin A11 (**1**), Figure S2: 13C NMR spectrum (126 MHz, chloroform-*d*) of xanthoquinodin A11 (**1**), Figure S3: HSQC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin A11 (**1**), Figure S4: COSY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin A11 (**1**), Figure S5: HMBC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin A11 (**1**), Figure S6: NOESY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin A11 (**1**), Figure S7: HRESIMS data of xanthoquinodin A11 (**1**), Figure S8: 1H NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B10 (**2**), Figure S9: 13C NMR spectrum (125 MHz, chloroform-*d*) of xanthoquinodin B10 (**2**), Figure S10: HSQC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B10 (**2**), Figure S11: COSY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B10 (**2**), Figure S12: HMBC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B10 (**2**), Figure S13: NOESY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B10 (**2**), Figure S14: HRESIMS data of xanthoquinodin B10 (**2**), Figure S15: 1H NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B11 (**3**), Figure S16: 13C NMR spectrum (125 MHz, chloroform-*d*) of xanthoquinodin B11 (**3**), Figure S17: HSQC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B11 (**3**), Figure S18: COSY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B11 (**3**), Figure S19: HMBC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B11 (**3**), Figure S20: NOESY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B11 (**3**), Figure S21: HRESIMS data of xanthoquinodin B11 (**3**), Figure S22: 1H NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B12 (**4**), Figure S23: 13C NMR spectrum (125 MHz, chloroform-*d*) of xanthoquinodin B12 (**4**), Figure S24: HSQC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B12 (**4**), Figure S25: COSY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B12 (**4**), Figure S26: HMBC NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B12 (**4**), Figure S27: NOESY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B12 (**4**), Figure S28: HRESIMS data of xanthoquinodin B12 (**4**), Figure S29: 1H NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B13 (**5**), Figure S30: 13C NMR spectrum (125 MHz, chloroform-*d*) of xanthoquinodin B13 (**5**), Figure S31: HSQC NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B13 (**5**), Figure S32: COSY NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B13 (**5**), Figure S33: HMBC NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B13 (**5**), Figure S34: NOESY NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B13 (**5**), Figure S35: HRESIMS data of xanthoquinodin B13 (**5**), Figure S36: 1H NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B14 (**6**), Figure S37: 13C NMR spectrum (176 MHz, chloroform-*d*) of xanthoquinodin B14 (**6**), Figure S38: HSQC NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B14 (**6**), Figure S39: COSY NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B14 (**6**), Figure S40: HMBC NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B14 (**6**), Figure S41: NOESY NMR spectrum (700 MHz, chloroform-*d*) of xanthoquinodin B14 (**6**), Figure S42: HRESIMS data of xanthoquinodin B14 (**6**), Figure S43: 1H NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B15 (**7**), Figure S44: 13C NMR spectrum (125 MHz, chloroform-*d*) of xanthoquinodin B15 (**7**), Figure S45: HSQC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B15 (**7**), Figure S46: COSY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B15 (**7**), Figure S47: HMBC NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B15 (**7**), Figure S48: NOESY NMR spectrum (500 MHz, chloroform-*d*) of xanthoquinodin B15 (**7**), Figure S49: HRESIMS data of xanthoquinodin B15 (**7**).

**Author Contributions:** Conceptualization, Y.M.-F. and F.S.; methodology, F.S., L.S. and Y.M.-F.; software, M.S.; formal analysis, F.S., L.S. and Y.M.-F.; investigation, F.S., L.S. and Y.M.-F.; visualization, L.S. and Y.M.-F.; resources, M.S. and A.M.S.; data curation, L.S. and Y.M.-F.; writing—original draft preparation, L.S. and Y.M.-F.; writing—review and editing, A.M.S., F.S. and M.S. All authors have read and agreed to the published version of the manuscript.

**Funding:** A joint PhD training program fellowship from University of Chinese Academy of Sciences (UCAS) was awarded to L.S., and Y.M.-F. was supported by a postdoctoral fellowship from Alexander-von-Humboldt Foundation, Germany.

**Acknowledgments:** The authors wish to thank Christel Kakoschke for recording the NMR spectra and Wera Collisi for conducting the bioassays.

**Conflicts of Interest:** The authors declare no conflict of interest.
